報告題目：3-Coordinate Organoboron Compounds Light the Way: Synthesis, Optical Properties and Cell Imaging
報告人：Todd B. Marder院士
報告時間：2019年11月16日（星期六）上午10
報告地點：長安校區啟翔樓233會議室
邀請人：紀雷教授
承辦學院：柔性電子研究院
聯系人：張倩文
聯系電話：88460889
報告摘要：
Three-coordinate boron, with a vacant pz-orbital and isoelectronic with a carbonium ion, can conjugate with organic π-systems as a strongp-acceptor in the excited state. Most 3-coordinate boron compounds are Lewis acidic, bind Lewis bases which disrupt this conjugation, and are sensitive to hydrolysis. Bulky substituents on B, such as mesityl (mes) groups, provide steric protection of the vacant p-orbital without disrupting the electronic communication with a π-system, resulting in compounds which are usually air and water stable. In aqueous solution, as required for biological applications, we require additional steric protection to avoid hydrolysis. We focus on the synthesis of dipolar, quadrupolar and octupolar compounds containing B(Ar)2groups, including those containing newp-acceptors considerably stronger than B(mes)2, and their linear and nonlinear (2nd and 3rd order NLO, TPA and TPEF) optical properties, and their applications, including one- and two-photo excited fluorescence imaging in live cells.
- J. He, T.B. Marder, et al. “N-Heterocyclic Olefins as Electron Donors in Combination with Triarylborane Acceptors: Synthesis, Optical and Electronic Properties of D-p-A Compounds,”Chem. Eur. J.,2019. DOI: 10.1002/chem.201903118.
- J. Merz, C. Lambert, T.B. Marder, et al. “Synthesis, Photophysical and Electronic Properties of Tetra- Donor- or Acceptor-Substituted ortho-Perylenes Displaying Four Reversible Oxidations or Reductions,”Chem. Sci.,201910, 7516.
- S. Griesbeck, C. Lambert, S. Yamaguchi, T.B. Marder, et al. "The Effect of Branching on One- and Two-Photon Absorption, Cell Viability and Localization of Cationic Triarylborane Chromophores with Dipolar vs. Octupolar Charge Distributions for Cellular Imaging,"Chem. Eur. J.,2019,25, 13164.
- X. Jia, C. Lambert, T.B. Marder, et al. “Triarylborane-Based Helical Donor-Acceptor Compounds: Synthesis, Photophysical and Electronic Properties,”Chem. Eur. J.,2019,25, 10845.
- S. Griesbeck, C. Lambert, S. Yamaguchi, T.B. Marder, et al. “Tuning thep-Bridge of Quadrupolar Triarylborane Chromophores for One- and Two-Photon Ecited Fluorescence Imaging of Lysosomes in Live Cells,”Chem. Sci.,2019,10, 5405.
- T.E. Stennett, T.B. Marder, H. Braunschweig, et al. “Near-Infrared Quadrupolar Chromophores Combining Three-Coordinate Boron-Based Superdonor and Superacceptor Units,”Angew. Chem. Int. Ed.,2019,58, 6449.
- S. Griesbeck, S. Yamaguchi, T.B. Marder, et al. “Optimization of Aqueous Stability versusp-Conjugation in Tetracationic Bis(triarylborane) Chromophores: Applications in Live-Cell Imaging,”Chem. Eur. J.,2019,25, 7679.
- L. Ji, T.B. Marder, et al. “Synthesis, Photophysical, and Electrochemical Properties of Pyrenes Substituted with Donors or Acceptors at the 4- or 4,9-Positions,”J. Org. Chem.,2018,83, 3599.
- J. Merz, C. Lambert, L. Ji, T.B. Marder, et al. “Pyrene MO Shuffle – Controlling Excited State and Redox Properties by Changing the Nature of the Frontier Orbitals,”Chem. Eur. J.,2017,23, 13164.
-S. Griesbeck, T. B. Marder, et al. “Water-Soluble Triarylborane Chromophores for One- and Two-Photon Excited Fluorescence Imaging of Mitochondria in Cells,”Chem. Eur. J.,2016,22, 14701.
- L. Ji, T.B. Marder, et al.“Electron Delocalization in Reduced Forms of 2-(BMes2)pyrene and 2,7-Bis(BMes2)pyrene,”J. Am. Chem. Soc.,2015,137, 6750.
- Z. Zhang, T. B. Marder, et al.“Taming the Beast: Fluoromesityl Groups Induce a Dramatic Stability Enhancement in Boroles,”Chem. Sci.,2015,6, 5922.
- Z. Zhang, T. B. Marder, et al.“D-π-A Triarylboron Compounds with Tunable Push-Pull Character Achieved by Modification of Both the Donor and Acceptor Moieties,”Chem. Eur. J.,2015, 21, 177.
- Z. Zhang, T.B. Marder, et al.“Optical and Electronic Properties of Air-stable Organoboron Compounds with Strongly Electron-accepting Bis(fluoromesityl)boryl Groups,”Chem. Sci.,2015, 6, 308.
- Reviews: L. Ji, S. Griesbeck, and T. B. Marder, “Recent Developments in and Perspectives on Three-Coordinate Boron Materials: A Bright Future,” Chem. Sci.,2017,8, 846; C.D. Entwistle and T.B. Marder, “Applications of Three-Coordinate Organoboron Compounds and Polymers in Optoelectronics,”Chem. Mater.,2004, 16, 4574; C.D. Entwistle and T.B. Marder, "Boron Chemistry Lights the Way: Optical Properties of Molecular and Polymeric Systems,"Angew. Chem. Int. Ed. Engl.,2002, 41, 2927.
報告人簡介：
Todd B. Marder，德國維爾茨堡大學化學系教授，歐洲科學院院士、巴伐利亞科學院院士、英國皇家化學會會士。Marder教授于1976年在麻省理工學院獲得學士學位、1981年在美國加利福尼亞大學獲得博士學位之后，先后任英國布里斯托大學從事博士后、杜邦化學高級研究員、加拿大滑鐵盧大學助理教授（1985）、副教授（1989），于1992年升任教授，1997年起任英國杜倫大學講席教授，2012年起任德國Universit?t Würzburg無機化學研究所講席教授。
Marder教授是國際知名金屬有機化學專家，其研究工作主要集中在金屬-硼及有機-硼化學(如過渡金屬催化的硼化反應、C-H鍵的選擇性功能化、有機硼光電功能材料等)，至今已在J. Am. Chem. Soc., Angew. Chem. Int. Ed.等國際頂級學術期刊上發表論文340多篇，被引超過22000次，H-index為83。Marder教授曾先后榮獲Royal Society of Chemistry Award in Main Group Element Chemistry (2008)及Royal Society Wolfson Research Merit Award (2010)等多項學術獎勵。Marder教授長期擔任Organometallics, Inorganic Chemistry、the Journal of Organometallic Chemistry、Polyhedron、Inorganica Chimica Acta、Applied Organometallic Chemistry、the Canadian Journal of Chemistry、the Chinese Journal of Chemistry、Crystal Engineering等國際學術期刊編委，應邀在國際學術會議或國際主流大學作學術報告300多場次，是英國杜倫大學、紐卡斯爾大學榮譽教授、香港科技大學、山東大學等多所高校的客座教授。
